A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin

Abstract Background Chemodynamic therapy (CDT) relying on intracellular iron ions and H2O2 is a promising therapeutic strategy due to its tumor selectivity, which is limited by the not enough metal ions or H2O2 supply of tumor microenvironment.Herein, we presented an efficient CDT strategy based on Chinese herbal monomer-dihydroartemisinin (DHA) as

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A Novel Framework to Predict Relative Habitat Selection in Aquatic Systems: Applying Machine Learning and Resource Selection Functions to Acoustic Telemetry Data From Multiple Shark Species

Resource selection functions (RSFs) have been widely applied to animal tracking data to examine relative habitat selection and to help guide management and conservation strategies.While readily used in terrestrial ecology, RSFs have yet to be Shin Guards extensively used within marine systems.As acoustic telemetry continues to be a pervasive approa

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Persistence of subclinical deformed wing virus infections in honeybees following Varroa mite removal and a bee population turnover.

Deformed wing virus (DWV) is a lethal virus of honeybees (Apis mellifera) implicated in elevated colony mortality rates worldwide and facilitated through vector transmission by the ectoparasitic mite Varroa destructor.Clinical, symptomatic DWV infections are almost exclusively associated with high virus titres during pupal development, usually acqu

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